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Differentiate w.r.t. x
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\frac{16^{-\frac{3}{2}}\left(x^{\frac{2}{3}}\right)^{-\frac{3}{2}}\left(y^{-2}\right)^{-\frac{3}{2}}}{2x^{-2}y}
Expand \left(16x^{\frac{2}{3}}y^{-2}\right)^{-\frac{3}{2}}.
\frac{16^{-\frac{3}{2}}x^{-1}\left(y^{-2}\right)^{-\frac{3}{2}}}{2x^{-2}y}
To raise a power to another power, multiply the exponents. Multiply \frac{2}{3} and -\frac{3}{2} to get -1.
\frac{16^{-\frac{3}{2}}x^{-1}y^{3}}{2x^{-2}y}
To raise a power to another power, multiply the exponents. Multiply -2 and -\frac{3}{2} to get 3.
\frac{\frac{1}{64}x^{-1}y^{3}}{2x^{-2}y}
Calculate 16 to the power of -\frac{3}{2} and get \frac{1}{64}.
\frac{\frac{1}{64}\times \frac{1}{x}y^{2}}{2x^{-2}}
Cancel out y in both numerator and denominator.
\frac{\frac{1}{64}x^{1}y^{2}}{2}
To divide powers of the same base, subtract the denominator's exponent from the numerator's exponent.
\frac{\frac{1}{64}xy^{2}}{2}
Calculate x to the power of 1 and get x.
\frac{1}{128}xy^{2}
Divide \frac{1}{64}xy^{2} by 2 to get \frac{1}{128}xy^{2}.