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Differentiate w.r.t. x
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\frac{-3x^{3}\times 2y^{2}\times 6y}{8x^{3}y\times 2xy^{3}}
To multiply powers of the same base, add their exponents. Add 2 and 1 to get 3.
\frac{-3x^{3}\times 2y^{3}\times 6}{8x^{3}y\times 2xy^{3}}
To multiply powers of the same base, add their exponents. Add 2 and 1 to get 3.
\frac{-3x^{3}\times 2y^{3}\times 6}{8x^{4}y\times 2y^{3}}
To multiply powers of the same base, add their exponents. Add 3 and 1 to get 4.
\frac{-3x^{3}\times 2y^{3}\times 6}{8x^{4}y^{4}\times 2}
To multiply powers of the same base, add their exponents. Add 1 and 3 to get 4.
\frac{-3\times 3}{2\times 2xy}
Cancel out 2\times 2x^{3}y^{3} in both numerator and denominator.
\frac{-9}{2\times 2xy}
Multiply -3 and 3 to get -9.
\frac{-9}{4xy}
Multiply 2 and 2 to get 4.
\frac{\mathrm{d}}{\mathrm{d}x}(\left(-\frac{36xy^{3}}{16xy^{4}}\right)x^{2-3})
To divide powers of the same base, subtract the denominator's exponent from the numerator's exponent.
\frac{\mathrm{d}}{\mathrm{d}x}(\left(-\frac{9}{4y}\right)\times \frac{1}{x})
Do the arithmetic.
-\left(-\frac{9}{4y}\right)x^{-1-1}
The derivative of a polynomial is the sum of the derivatives of its terms. The derivative of a constant term is 0. The derivative of ax^{n} is nax^{n-1}.
\frac{9}{4y}x^{-2}
Do the arithmetic.