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\frac{-19683\times 32^{-2}\left(-8\right)^{4}\times 25^{2}}{\left(-72\right)^{4}\left(-50^{3}\right)^{4}}
Calculate -27 to the power of 3 and get -19683.
\frac{-19683\times \frac{1}{1024}\left(-8\right)^{4}\times 25^{2}}{\left(-72\right)^{4}\left(-50^{3}\right)^{4}}
Calculate 32 to the power of -2 and get \frac{1}{1024}.
\frac{-\frac{19683}{1024}\left(-8\right)^{4}\times 25^{2}}{\left(-72\right)^{4}\left(-50^{3}\right)^{4}}
Multiply -19683 and \frac{1}{1024} to get -\frac{19683}{1024}.
\frac{-\frac{19683}{1024}\times 4096\times 25^{2}}{\left(-72\right)^{4}\left(-50^{3}\right)^{4}}
Calculate -8 to the power of 4 and get 4096.
\frac{-78732\times 25^{2}}{\left(-72\right)^{4}\left(-50^{3}\right)^{4}}
Multiply -\frac{19683}{1024} and 4096 to get -78732.
\frac{-78732\times 625}{\left(-72\right)^{4}\left(-50^{3}\right)^{4}}
Calculate 25 to the power of 2 and get 625.
\frac{-49207500}{\left(-72\right)^{4}\left(-50^{3}\right)^{4}}
Multiply -78732 and 625 to get -49207500.
\frac{-49207500}{26873856\left(-50^{3}\right)^{4}}
Calculate -72 to the power of 4 and get 26873856.
\frac{-49207500}{26873856\left(-125000\right)^{4}}
Calculate 50 to the power of 3 and get 125000.
\frac{-49207500}{26873856\times 244140625000000000000}
Calculate -125000 to the power of 4 and get 244140625000000000000.
\frac{-49207500}{6561000000000000000000000000}
Multiply 26873856 and 244140625000000000000 to get 6561000000000000000000000000.
-\frac{3}{400000000000000000000}
Reduce the fraction \frac{-49207500}{6561000000000000000000000000} to lowest terms by extracting and canceling out 16402500.