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\frac{-2x^{2}z^{5}}{3y}\times \left(\frac{\left(3xy^{2}z^{2}\right)^{5}\left(-2x^{3}z\right)^{-2}}{\left(6x^{4}y^{3}z^{5}\right)^{-4}}\right)^{2}
Cancel out x^{2}y^{3} in both numerator and denominator.
\frac{-2x^{2}z^{5}}{3y}\times \left(\frac{3^{5}x^{5}\left(y^{2}\right)^{5}\left(z^{2}\right)^{5}\left(-2x^{3}z\right)^{-2}}{\left(6x^{4}y^{3}z^{5}\right)^{-4}}\right)^{2}
Expand \left(3xy^{2}z^{2}\right)^{5}.
\frac{-2x^{2}z^{5}}{3y}\times \left(\frac{3^{5}x^{5}y^{10}\left(z^{2}\right)^{5}\left(-2x^{3}z\right)^{-2}}{\left(6x^{4}y^{3}z^{5}\right)^{-4}}\right)^{2}
To raise a power to another power, multiply the exponents. Multiply 2 and 5 to get 10.
\frac{-2x^{2}z^{5}}{3y}\times \left(\frac{3^{5}x^{5}y^{10}z^{10}\left(-2x^{3}z\right)^{-2}}{\left(6x^{4}y^{3}z^{5}\right)^{-4}}\right)^{2}
To raise a power to another power, multiply the exponents. Multiply 2 and 5 to get 10.
\frac{-2x^{2}z^{5}}{3y}\times \left(\frac{243x^{5}y^{10}z^{10}\left(-2x^{3}z\right)^{-2}}{\left(6x^{4}y^{3}z^{5}\right)^{-4}}\right)^{2}
Calculate 3 to the power of 5 and get 243.
\frac{-2x^{2}z^{5}}{3y}\times \left(\frac{243x^{5}y^{10}z^{10}\left(-2\right)^{-2}\left(x^{3}\right)^{-2}z^{-2}}{\left(6x^{4}y^{3}z^{5}\right)^{-4}}\right)^{2}
Expand \left(-2x^{3}z\right)^{-2}.
\frac{-2x^{2}z^{5}}{3y}\times \left(\frac{243x^{5}y^{10}z^{10}\left(-2\right)^{-2}x^{-6}z^{-2}}{\left(6x^{4}y^{3}z^{5}\right)^{-4}}\right)^{2}
To raise a power to another power, multiply the exponents. Multiply 3 and -2 to get -6.
\frac{-2x^{2}z^{5}}{3y}\times \left(\frac{243x^{5}y^{10}z^{10}\times \frac{1}{4}x^{-6}z^{-2}}{\left(6x^{4}y^{3}z^{5}\right)^{-4}}\right)^{2}
Calculate -2 to the power of -2 and get \frac{1}{4}.
\frac{-2x^{2}z^{5}}{3y}\times \left(\frac{\frac{243}{4}x^{5}y^{10}z^{10}x^{-6}z^{-2}}{\left(6x^{4}y^{3}z^{5}\right)^{-4}}\right)^{2}
Multiply 243 and \frac{1}{4} to get \frac{243}{4}.
\frac{-2x^{2}z^{5}}{3y}\times \left(\frac{\frac{243}{4}x^{-1}y^{10}z^{10}z^{-2}}{\left(6x^{4}y^{3}z^{5}\right)^{-4}}\right)^{2}
To multiply powers of the same base, add their exponents. Add 5 and -6 to get -1.
\frac{-2x^{2}z^{5}}{3y}\times \left(\frac{\frac{243}{4}x^{-1}y^{10}z^{8}}{\left(6x^{4}y^{3}z^{5}\right)^{-4}}\right)^{2}
To multiply powers of the same base, add their exponents. Add 10 and -2 to get 8.
\frac{-2x^{2}z^{5}}{3y}\times \left(\frac{\frac{243}{4}x^{-1}y^{10}z^{8}}{6^{-4}\left(x^{4}\right)^{-4}\left(y^{3}\right)^{-4}\left(z^{5}\right)^{-4}}\right)^{2}
Expand \left(6x^{4}y^{3}z^{5}\right)^{-4}.
\frac{-2x^{2}z^{5}}{3y}\times \left(\frac{\frac{243}{4}x^{-1}y^{10}z^{8}}{6^{-4}x^{-16}\left(y^{3}\right)^{-4}\left(z^{5}\right)^{-4}}\right)^{2}
To raise a power to another power, multiply the exponents. Multiply 4 and -4 to get -16.
\frac{-2x^{2}z^{5}}{3y}\times \left(\frac{\frac{243}{4}x^{-1}y^{10}z^{8}}{6^{-4}x^{-16}y^{-12}\left(z^{5}\right)^{-4}}\right)^{2}
To raise a power to another power, multiply the exponents. Multiply 3 and -4 to get -12.
\frac{-2x^{2}z^{5}}{3y}\times \left(\frac{\frac{243}{4}x^{-1}y^{10}z^{8}}{6^{-4}x^{-16}y^{-12}z^{-20}}\right)^{2}
To raise a power to another power, multiply the exponents. Multiply 5 and -4 to get -20.
\frac{-2x^{2}z^{5}}{3y}\times \left(\frac{\frac{243}{4}x^{-1}y^{10}z^{8}}{\frac{1}{1296}x^{-16}y^{-12}z^{-20}}\right)^{2}
Calculate 6 to the power of -4 and get \frac{1}{1296}.
\frac{-2x^{2}z^{5}}{3y}\times \left(\frac{\frac{243}{4}x^{15}y^{22}z^{28}}{\frac{1}{1296}}\right)^{2}
To divide powers of the same base, subtract the denominator's exponent from the numerator's exponent.
\frac{-2x^{2}z^{5}}{3y}\times \left(\frac{243}{4}x^{15}y^{22}z^{28}\times 1296\right)^{2}
Divide \frac{243}{4}x^{15}y^{22}z^{28} by \frac{1}{1296} by multiplying \frac{243}{4}x^{15}y^{22}z^{28} by the reciprocal of \frac{1}{1296}.
\frac{-2x^{2}z^{5}}{3y}\times \left(\frac{243}{4}\right)^{2}\left(x^{15}\right)^{2}\left(y^{22}\right)^{2}\left(z^{28}\right)^{2}\times 1296^{2}
Expand \left(\frac{243}{4}x^{15}y^{22}z^{28}\times 1296\right)^{2}.
\frac{-2x^{2}z^{5}}{3y}\times \left(\frac{243}{4}\right)^{2}x^{30}\left(y^{22}\right)^{2}\left(z^{28}\right)^{2}\times 1296^{2}
To raise a power to another power, multiply the exponents. Multiply 15 and 2 to get 30.
\frac{-2x^{2}z^{5}}{3y}\times \left(\frac{243}{4}\right)^{2}x^{30}y^{44}\left(z^{28}\right)^{2}\times 1296^{2}
To raise a power to another power, multiply the exponents. Multiply 22 and 2 to get 44.
\frac{-2x^{2}z^{5}}{3y}\times \left(\frac{243}{4}\right)^{2}x^{30}y^{44}z^{56}\times 1296^{2}
To raise a power to another power, multiply the exponents. Multiply 28 and 2 to get 56.
\frac{-2x^{2}z^{5}}{3y}\times \frac{59049}{16}x^{30}y^{44}z^{56}\times 1296^{2}
Calculate \frac{243}{4} to the power of 2 and get \frac{59049}{16}.
\frac{-2x^{2}z^{5}}{3y}\times \frac{59049}{16}x^{30}y^{44}z^{56}\times 1679616
Calculate 1296 to the power of 2 and get 1679616.
\frac{-2x^{2}z^{5}}{3y}\times 6198727824x^{30}y^{44}z^{56}
Multiply \frac{59049}{16} and 1679616 to get 6198727824.
\frac{-2x^{2}z^{5}\times 6198727824}{3y}x^{30}y^{44}z^{56}
Express \frac{-2x^{2}z^{5}}{3y}\times 6198727824 as a single fraction.
\frac{-2\times 2066242608x^{2}z^{5}}{y}x^{30}y^{44}z^{56}
Cancel out 3 in both numerator and denominator.
\frac{-2\times 2066242608x^{2}z^{5}x^{30}}{y}y^{44}z^{56}
Express \frac{-2\times 2066242608x^{2}z^{5}}{y}x^{30} as a single fraction.
\frac{-2\times 2066242608x^{2}z^{5}x^{30}y^{44}}{y}z^{56}
Express \frac{-2\times 2066242608x^{2}z^{5}x^{30}}{y}y^{44} as a single fraction.
-2\times 2066242608x^{2}z^{5}x^{30}y^{43}z^{56}
Cancel out y in both numerator and denominator.
-2\times 2066242608x^{32}z^{5}y^{43}z^{56}
To multiply powers of the same base, add their exponents. Add 2 and 30 to get 32.
-4132485216x^{32}z^{5}y^{43}z^{56}
Multiply -2 and 2066242608 to get -4132485216.
-4132485216x^{32}z^{61}y^{43}
To multiply powers of the same base, add their exponents. Add 5 and 56 to get 61.
\frac{-2x^{2}z^{5}}{3y}\times \left(\frac{\left(3xy^{2}z^{2}\right)^{5}\left(-2x^{3}z\right)^{-2}}{\left(6x^{4}y^{3}z^{5}\right)^{-4}}\right)^{2}
Cancel out x^{2}y^{3} in both numerator and denominator.
\frac{-2x^{2}z^{5}}{3y}\times \left(\frac{3^{5}x^{5}\left(y^{2}\right)^{5}\left(z^{2}\right)^{5}\left(-2x^{3}z\right)^{-2}}{\left(6x^{4}y^{3}z^{5}\right)^{-4}}\right)^{2}
Expand \left(3xy^{2}z^{2}\right)^{5}.
\frac{-2x^{2}z^{5}}{3y}\times \left(\frac{3^{5}x^{5}y^{10}\left(z^{2}\right)^{5}\left(-2x^{3}z\right)^{-2}}{\left(6x^{4}y^{3}z^{5}\right)^{-4}}\right)^{2}
To raise a power to another power, multiply the exponents. Multiply 2 and 5 to get 10.
\frac{-2x^{2}z^{5}}{3y}\times \left(\frac{3^{5}x^{5}y^{10}z^{10}\left(-2x^{3}z\right)^{-2}}{\left(6x^{4}y^{3}z^{5}\right)^{-4}}\right)^{2}
To raise a power to another power, multiply the exponents. Multiply 2 and 5 to get 10.
\frac{-2x^{2}z^{5}}{3y}\times \left(\frac{243x^{5}y^{10}z^{10}\left(-2x^{3}z\right)^{-2}}{\left(6x^{4}y^{3}z^{5}\right)^{-4}}\right)^{2}
Calculate 3 to the power of 5 and get 243.
\frac{-2x^{2}z^{5}}{3y}\times \left(\frac{243x^{5}y^{10}z^{10}\left(-2\right)^{-2}\left(x^{3}\right)^{-2}z^{-2}}{\left(6x^{4}y^{3}z^{5}\right)^{-4}}\right)^{2}
Expand \left(-2x^{3}z\right)^{-2}.
\frac{-2x^{2}z^{5}}{3y}\times \left(\frac{243x^{5}y^{10}z^{10}\left(-2\right)^{-2}x^{-6}z^{-2}}{\left(6x^{4}y^{3}z^{5}\right)^{-4}}\right)^{2}
To raise a power to another power, multiply the exponents. Multiply 3 and -2 to get -6.
\frac{-2x^{2}z^{5}}{3y}\times \left(\frac{243x^{5}y^{10}z^{10}\times \frac{1}{4}x^{-6}z^{-2}}{\left(6x^{4}y^{3}z^{5}\right)^{-4}}\right)^{2}
Calculate -2 to the power of -2 and get \frac{1}{4}.
\frac{-2x^{2}z^{5}}{3y}\times \left(\frac{\frac{243}{4}x^{5}y^{10}z^{10}x^{-6}z^{-2}}{\left(6x^{4}y^{3}z^{5}\right)^{-4}}\right)^{2}
Multiply 243 and \frac{1}{4} to get \frac{243}{4}.
\frac{-2x^{2}z^{5}}{3y}\times \left(\frac{\frac{243}{4}x^{-1}y^{10}z^{10}z^{-2}}{\left(6x^{4}y^{3}z^{5}\right)^{-4}}\right)^{2}
To multiply powers of the same base, add their exponents. Add 5 and -6 to get -1.
\frac{-2x^{2}z^{5}}{3y}\times \left(\frac{\frac{243}{4}x^{-1}y^{10}z^{8}}{\left(6x^{4}y^{3}z^{5}\right)^{-4}}\right)^{2}
To multiply powers of the same base, add their exponents. Add 10 and -2 to get 8.
\frac{-2x^{2}z^{5}}{3y}\times \left(\frac{\frac{243}{4}x^{-1}y^{10}z^{8}}{6^{-4}\left(x^{4}\right)^{-4}\left(y^{3}\right)^{-4}\left(z^{5}\right)^{-4}}\right)^{2}
Expand \left(6x^{4}y^{3}z^{5}\right)^{-4}.
\frac{-2x^{2}z^{5}}{3y}\times \left(\frac{\frac{243}{4}x^{-1}y^{10}z^{8}}{6^{-4}x^{-16}\left(y^{3}\right)^{-4}\left(z^{5}\right)^{-4}}\right)^{2}
To raise a power to another power, multiply the exponents. Multiply 4 and -4 to get -16.
\frac{-2x^{2}z^{5}}{3y}\times \left(\frac{\frac{243}{4}x^{-1}y^{10}z^{8}}{6^{-4}x^{-16}y^{-12}\left(z^{5}\right)^{-4}}\right)^{2}
To raise a power to another power, multiply the exponents. Multiply 3 and -4 to get -12.
\frac{-2x^{2}z^{5}}{3y}\times \left(\frac{\frac{243}{4}x^{-1}y^{10}z^{8}}{6^{-4}x^{-16}y^{-12}z^{-20}}\right)^{2}
To raise a power to another power, multiply the exponents. Multiply 5 and -4 to get -20.
\frac{-2x^{2}z^{5}}{3y}\times \left(\frac{\frac{243}{4}x^{-1}y^{10}z^{8}}{\frac{1}{1296}x^{-16}y^{-12}z^{-20}}\right)^{2}
Calculate 6 to the power of -4 and get \frac{1}{1296}.
\frac{-2x^{2}z^{5}}{3y}\times \left(\frac{\frac{243}{4}x^{15}y^{22}z^{28}}{\frac{1}{1296}}\right)^{2}
To divide powers of the same base, subtract the denominator's exponent from the numerator's exponent.
\frac{-2x^{2}z^{5}}{3y}\times \left(\frac{243}{4}x^{15}y^{22}z^{28}\times 1296\right)^{2}
Divide \frac{243}{4}x^{15}y^{22}z^{28} by \frac{1}{1296} by multiplying \frac{243}{4}x^{15}y^{22}z^{28} by the reciprocal of \frac{1}{1296}.
\frac{-2x^{2}z^{5}}{3y}\times \left(\frac{243}{4}\right)^{2}\left(x^{15}\right)^{2}\left(y^{22}\right)^{2}\left(z^{28}\right)^{2}\times 1296^{2}
Expand \left(\frac{243}{4}x^{15}y^{22}z^{28}\times 1296\right)^{2}.
\frac{-2x^{2}z^{5}}{3y}\times \left(\frac{243}{4}\right)^{2}x^{30}\left(y^{22}\right)^{2}\left(z^{28}\right)^{2}\times 1296^{2}
To raise a power to another power, multiply the exponents. Multiply 15 and 2 to get 30.
\frac{-2x^{2}z^{5}}{3y}\times \left(\frac{243}{4}\right)^{2}x^{30}y^{44}\left(z^{28}\right)^{2}\times 1296^{2}
To raise a power to another power, multiply the exponents. Multiply 22 and 2 to get 44.
\frac{-2x^{2}z^{5}}{3y}\times \left(\frac{243}{4}\right)^{2}x^{30}y^{44}z^{56}\times 1296^{2}
To raise a power to another power, multiply the exponents. Multiply 28 and 2 to get 56.
\frac{-2x^{2}z^{5}}{3y}\times \frac{59049}{16}x^{30}y^{44}z^{56}\times 1296^{2}
Calculate \frac{243}{4} to the power of 2 and get \frac{59049}{16}.
\frac{-2x^{2}z^{5}}{3y}\times \frac{59049}{16}x^{30}y^{44}z^{56}\times 1679616
Calculate 1296 to the power of 2 and get 1679616.
\frac{-2x^{2}z^{5}}{3y}\times 6198727824x^{30}y^{44}z^{56}
Multiply \frac{59049}{16} and 1679616 to get 6198727824.
\frac{-2x^{2}z^{5}\times 6198727824}{3y}x^{30}y^{44}z^{56}
Express \frac{-2x^{2}z^{5}}{3y}\times 6198727824 as a single fraction.
\frac{-2\times 2066242608x^{2}z^{5}}{y}x^{30}y^{44}z^{56}
Cancel out 3 in both numerator and denominator.
\frac{-2\times 2066242608x^{2}z^{5}x^{30}}{y}y^{44}z^{56}
Express \frac{-2\times 2066242608x^{2}z^{5}}{y}x^{30} as a single fraction.
\frac{-2\times 2066242608x^{2}z^{5}x^{30}y^{44}}{y}z^{56}
Express \frac{-2\times 2066242608x^{2}z^{5}x^{30}}{y}y^{44} as a single fraction.
-2\times 2066242608x^{2}z^{5}x^{30}y^{43}z^{56}
Cancel out y in both numerator and denominator.
-2\times 2066242608x^{32}z^{5}y^{43}z^{56}
To multiply powers of the same base, add their exponents. Add 2 and 30 to get 32.
-4132485216x^{32}z^{5}y^{43}z^{56}
Multiply -2 and 2066242608 to get -4132485216.
-4132485216x^{32}z^{61}y^{43}
To multiply powers of the same base, add their exponents. Add 5 and 56 to get 61.