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factor(\frac{\frac{1}{216}\times 108\left(25x^{2}+108\right)x^{3}}{2x^{3}}-\left(\left(\frac{5}{2}x-8\right)^{2}+4\left(10x+1\right)\right))
Factor the expressions that are not already factored in \frac{\left(\frac{5}{6}x^{2}+3x\right)^{3}-\left(\frac{5}{6}x^{2}-3x\right)^{3}}{2x^{3}}.
factor(\frac{1}{216}\times 54\left(25x^{2}+108\right)-\left(\left(\frac{5}{2}x-8\right)^{2}+4\left(10x+1\right)\right))
Cancel out 2x^{3} in both numerator and denominator.
factor(\frac{25}{4}x^{2}+27-\left(\left(\frac{5}{2}x-8\right)^{2}+4\left(10x+1\right)\right))
Expand the expression.
factor(\frac{25}{4}x^{2}+27-\left(\left(\frac{5}{2}x-8\right)^{2}+40x+4\right))
Use the distributive property to multiply 4 by 10x+1.
factor(\frac{25}{4}x^{2}+27-\left(\frac{5}{2}x-8\right)^{2}-40x-4)
To find the opposite of \left(\frac{5}{2}x-8\right)^{2}+40x+4, find the opposite of each term.
factor(\frac{25}{4}x^{2}+23-\left(\frac{5}{2}x-8\right)^{2}-40x)
Subtract 4 from 27 to get 23.
\frac{25x^{2}+92-\left(5x-16\right)^{2}-160x}{4}
Factor out \frac{1}{4}.
-41
Simplify.