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Differentiate w.r.t. x
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\frac{\left(4x^{-2}\right)^{-\frac{5}{2}}}{\left(9y^{-4}\right)^{-\frac{5}{2}}}
To raise \frac{4x^{-2}}{9y^{-4}} to a power, raise both numerator and denominator to the power and then divide.
\frac{4^{-\frac{5}{2}}\left(x^{-2}\right)^{-\frac{5}{2}}}{\left(9y^{-4}\right)^{-\frac{5}{2}}}
Expand \left(4x^{-2}\right)^{-\frac{5}{2}}.
\frac{4^{-\frac{5}{2}}x^{5}}{\left(9y^{-4}\right)^{-\frac{5}{2}}}
To raise a power to another power, multiply the exponents. Multiply -2 and -\frac{5}{2} to get 5.
\frac{\frac{1}{32}x^{5}}{\left(9y^{-4}\right)^{-\frac{5}{2}}}
Calculate 4 to the power of -\frac{5}{2} and get \frac{1}{32}.
\frac{\frac{1}{32}x^{5}}{9^{-\frac{5}{2}}\left(y^{-4}\right)^{-\frac{5}{2}}}
Expand \left(9y^{-4}\right)^{-\frac{5}{2}}.
\frac{\frac{1}{32}x^{5}}{9^{-\frac{5}{2}}y^{10}}
To raise a power to another power, multiply the exponents. Multiply -4 and -\frac{5}{2} to get 10.
\frac{\frac{1}{32}x^{5}}{\frac{1}{243}y^{10}}
Calculate 9 to the power of -\frac{5}{2} and get \frac{1}{243}.