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16x^{2}+24x+9-2\left(5x-3\right)\left(x+1\right)-2x\left(3x+10\right)
Use binomial theorem \left(a+b\right)^{2}=a^{2}+2ab+b^{2} to expand \left(4x+3\right)^{2}.
16x^{2}+24x+9+\left(-10x+6\right)\left(x+1\right)-2x\left(3x+10\right)
Use the distributive property to multiply -2 by 5x-3.
16x^{2}+24x+9-10x^{2}-4x+6-2x\left(3x+10\right)
Use the distributive property to multiply -10x+6 by x+1 and combine like terms.
6x^{2}+24x+9-4x+6-2x\left(3x+10\right)
Combine 16x^{2} and -10x^{2} to get 6x^{2}.
6x^{2}+20x+9+6-2x\left(3x+10\right)
Combine 24x and -4x to get 20x.
6x^{2}+20x+15-2x\left(3x+10\right)
Add 9 and 6 to get 15.
6x^{2}+20x+15-6x^{2}-20x
Use the distributive property to multiply -2x by 3x+10.
20x+15-20x
Combine 6x^{2} and -6x^{2} to get 0.
15
Combine 20x and -20x to get 0.