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\frac{22-5\times \frac{1}{1000}}{\left(4.5\times 10^{-3}\right)^{2}}
Calculate 10 to the power of -3 and get \frac{1}{1000}.
\frac{22-\frac{1}{200}}{\left(4.5\times 10^{-3}\right)^{2}}
Multiply 5 and \frac{1}{1000} to get \frac{1}{200}.
\frac{\frac{4399}{200}}{\left(4.5\times 10^{-3}\right)^{2}}
Subtract \frac{1}{200} from 22 to get \frac{4399}{200}.
\frac{\frac{4399}{200}}{\left(4.5\times \frac{1}{1000}\right)^{2}}
Calculate 10 to the power of -3 and get \frac{1}{1000}.
\frac{\frac{4399}{200}}{\left(\frac{9}{2000}\right)^{2}}
Multiply 4.5 and \frac{1}{1000} to get \frac{9}{2000}.
\frac{\frac{4399}{200}}{\frac{81}{4000000}}
Calculate \frac{9}{2000} to the power of 2 and get \frac{81}{4000000}.
\frac{4399}{200}\times \frac{4000000}{81}
Divide \frac{4399}{200} by \frac{81}{4000000} by multiplying \frac{4399}{200} by the reciprocal of \frac{81}{4000000}.
\frac{87980000}{81}
Multiply \frac{4399}{200} and \frac{4000000}{81} to get \frac{87980000}{81}.