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Differentiate w.r.t. a
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\frac{\mathrm{d}}{\mathrm{d}a}(-3a^{4})
Combine a^{4} and -4a^{4} to get -3a^{4}.
4\left(-3\right)a^{4-1}
The derivative of ax^{n} is nax^{n-1}.
-12a^{4-1}
Multiply 4 times -3.
-12a^{3}
Subtract 1 from 4.
-3a^{4}
Combine a^{4} and -4a^{4} to get -3a^{4}.